Endocannabinoid Deficiency using CBD oil

How Does The Endocannabinoid System Regulate Inflammation?

When an infection attacks the human body’s immune system, it reacts with inflammation as a natural protective measure. The inflammation helps reduce damage to the tissue. It also acts as a disinfectant to clean the affected area of any pathogens and germs. Inflammation happens as the immune cells, and fluid cells start the process of homeostasis in the infected area.

However, inflammation must lessen once the infection has cleared off, or else it can become toxic to the body. If the immune system is activated, conditions such as auto-immune disease or chronic inflammations can happen. This is where retrograde signals come in handy. They fire messages that inform the immune cells to withdraw from the recently healed area and reduce the inflammation.

Many products, including CBD, have recently come on the market and it’s important to understand the science of how those products affect the endocannabinoid system before selling/reselling products. After reviewing this post, you’ll be better equipped to how starting an online CBD business impacts the endocannabinoid system of your customers.

Endocannabinoid Deficiency: What Is It?

Endocannabinoid deficiency is a medical theory posited by Dr. Ethan Russo., the Director of Research and Development of the International Cannabis and Cannabinoids Institute (ICCI). It connects lower levels of endocannabinoids and improper functioning of the endocannabinoid system to several common ailments. 

Conditions and symptoms like irritable bowel syndrome, migraines, and fibromyalgia are all thought to be impacted or caused by an endocannabinoid deficiency. Most of the conditions linked to poor ECS functioning are usually thought of as chronic and incurable. Sufferers can expect to deal with symptoms for the rest of their lives. 

But now, Clinical Endocannabinoid Deficiency (CED) offers some home for those with chronic illnesses. Russo suggests that since most of these ailments are acquired rather than congenital, a disturbance to the ECS is to blame. If that’s true, then it opens up the possibility for relief or reversal down the road. 

Current Theories

Dr. Russo was the first to pose the theory of CED back in 2001. He’s continued study in the area since then, publishing several additional papers on the subject. 

His 2016 paper, “Clinical Endocannabinoid Deficiency Reconsidered,” he came back to the topic with a new perspective based on additional, substantive evidence found over the years. 

He outlined three new points:

  1. Migraine sufferers showed statistically significant depressed levels of anandamide.
  2. PTSD sufferers showed decreased levels of ECS functioning.
  3. Clinical data showed that lifestyle changes and cannabinoid treatment produced evidence of better sleep, improved pain levels, and other benefits.

While Russo’s study mainly focused on migraines, IBS, and fibromyalgia, there are additional illnesses that are also being classified underneath CED. These include, but are not limited to:

  • Glaucoma
  • PTSD
  • Colic
  • Repeated miscarriages
  • Phantom pain
  • Neuropathy
  • Cystic fibrosis
  • Bipolar disorder
  • Hyperemesis gravidarum

While there’s still much to be learned about the inner-workings of the ECS and how CED might influence common chronic illness, current research points toward hope for relief, treatment, or even reversal somewhere down the road. 

Future Research

The identification of the ECS is so new that many physicians actively practicing today have very little background in it. Further research is now necessary for us to understand the severity of ECS’s role in everyday biological functions. 

Over the past ten years or so, ECS has become the target focus of many scientific studies. Researchers have looked into its implications in different physiological conditions in both peripheral and central nervous systems.  

Further down the road, cannabinoid researchers hope to learn more about how modulating ECS activity affects a wide range of conditions. Some specific conditions to be studied include:

  • Hypertension
  • Obesity
  • Osteoporosis
  • Huntington’s disease
  • Parkinson’s
  • Anxiety and mood disorders
  • Multiple sclerosis
  • Stroke
  • Spinal Cord Injury

Some scientists also expect to study the use of plant-derived cannabinoids to modify and regulate the ECS and, thus, improve symptoms.

Some research shows this to be a useful tactic to reduce anxiety disorders.

What is endocannabinoid deficiency? In short, endocannabinoid deficiency is a medical theory that links decreased levels of endocannabinoids and improper functioning of the endocannabinoid system to many chronic disorders. 

Since the endocannabinoid system is found within almost every other biological system, it has the potential to impact and interfere with several physiological processes.

Hemp Seed Oil for Breakfast

How Hemp Seed Oil Drives Us

Hemp seeds have been used as a food product for centuries, so its use is widespread and standardized. In bakeries, they use it for certain savory fritters such as sunflower seeds as well as canary seed to feed canaries, which also often contain hemp seed oil.

Today, the use of these seeds to make different products is beginning to expand considerably thanks to the cannabis boom that we are currently experiencing. This does not mean that they were not used before, but that today they are simply more visible. Why is that? On the one hand, because of the acceptance of marijuana and hemp products (eg the CBD Oils, retail medical marijuana and wholesale hemp bombs) by society and, on the other hand, mainly because of the interest was shown by large corporations.

Hemp fields

There are still some people who are wary of hemp oil because the plant that produces the seeds from which the oil is extracted is from the same family as the cannabis plant.

Consequently, these people think that consuming the oil from these seeds will produce psychotropic effects and therefore do not consider its consumption. But what would they say if we told them that hemp oil is considered to be the best oil in the world, leaving extra virgin olive oil and even more so– sunflower oil– far behind? To make this clearer for you, we will continue to talk to you about the properties and benefits of this mysterious oil.

Where does hemp seed oil come from? 

Obviously, as its name indicates, it is extracted from the seeds of the industrial hemp crop, completely legal and fit for consumption.

This type of exploitation is possible thanks to the control of the levels of THC produced by the hemp plants, which must in no case exceed 0.3%. Moreover, only a few varieties are authorized for their cultivation and the commercialization of their derived products.

How is hemp seed oil obtained?

 To obtain this healthy and fantastic oil, the seeds are simply used, although not all varieties of industrial hemp are ideal for oil extraction.

In fact, for a variety to be ideal for oil production, it must be a large seed producer, which must be large enough to produce more oil compared to plants that produce smaller seeds.

To extract the oil, the technique of cold pressing is often used, which helps to keep all the properties of the oil contained in the seeds intact. This type of extraction technique, carried out at low temperatures, is often used in the food industry, too.

What are the benefits of hemp seed oil? 

One of the benefits that stand out the most in its daily consumption is the reduced risk of suffering from cardiovascular disease. It also has other useful benefits that researchers are only beginning to fully discover.

It should also be noted that it has an infinite number of benefits for skin and scalp care. Due to its moisturizing and antioxidant properties, hemp seed oil is a good option to be applied to the skin and hair daily.

For you to better appreciate all its benefits, we list below the most important ones.

Health benefits

  • Great source of protein
  • Great source of essential fatty acids
  • Moisturizes skin and hair
  • Relieves and calms various skin infections (itching, eczema, psoriasis, acne, dandruff, dry skin)
  • Improves and strengthens the appearance of the nails
  • Prevents premature aging of the skin due to its anti-oxidant action.
  • Improves the immune system
  • Offers light protection against the sun
  • Helps fight skin infections
  • Accelerates wound healing
  • Prevents the appearance of stretch marks
  • Prevents the onset of cardiovascular disease
  • Helps to treat fibromyalgia

How to consume hemp seed oil

This brings us to the simplest part of the article since to enjoy its fantastic benefits, all you need to do is ingest two spoons a day. Or if you prefer, you can simply season your salads with it or any other type of food.

The only drawback is that it is not suitable for frying. It loses its properties at a lower temperature than olive oil. It is therefore not recommended to cook with it. 


 Hemp oil should be present in all the cuisines of the world and should be part of our daily life, whether as a seasoning, consumed directly at breakfast with a pair of teaspoons or externally for skincare.

The benefits it provides are very interesting at different levels and also, it has the best level of omega 3 and 6, which makes it one of the best oils in the world for human consumption.

bar chart from USDA draft about CBD

USDA Provides Interim Measures for Hemp Production

A new draft by the USDA provides some insights for where the cannabis industry might be headed as regulatory concerns are finally being addressed at the federal level. The draft focuses on the production of hemp, in general, though comments on specific products such as cannabidiol (CBD), too, as the Farm Bill of 2018 has caused doors to open for the selling of CBD across the nation.

Within the USDA’s draft, they mention, “Producer interest in hemp production is largely driven by the potential for high returns from sales of hemp flowers to be processed into CBD oil.” The CBD oil market is certainly booming in many localities in the United States and the USDA is addressing the concern as the demand has increased for the CBD Oil product comparative to other cash crops.

Interestingly, the USDA states, “If FDA does not provide clarity about their plans for future regulation of CBD, there will continue to be uncertainty and downward pressure on the CBD portion of the hemp market.” This (and other statements in the draft) might cause the pressure that the market has been seeking to place for clearer guidelines from the FDA in the coming months.

Only time will tell whether the FDA will take notice of the demand-for-answers that the USDA seems to be prompting. As the industry watches, it seems like answers to the questions concerning legality and categorization of CBD (on the federal level) may be coming soon.

If you notice other regulatory updates in the industry and would like to see them posted on the blog, please contact us to let us know.

Obtaining the right hemp seeds is paramound in your commercial cultivation business plan

On Commercial Cultivation Business Plan — it’s a lengthy process

From initial approval to grow hemp, to the growing process to growing hemp and drying it out ready to be used; it takes a while to start a commercial cultivation business. In this posts, we’ll get you started for starting your business plan.

As mentioned in a recent article, it’s quite common that farmers “don’t have a harvest plan.” It’s a shame. If you’re looking to start your grow for the 2020s, you have to start thinking now about how your hemp business will succeed in the coming years. Below are the elements for a commercial cultivation business plan.

Elements of a Business Plan

When it comes to developing your business plan, you need to understand who the plan is ultimately for– is it for you and your business partners or is it for obtaining investors into your venture?

Here are some of the elements that your plan should include:

  1. Executive Summary
  2. Company Overview
  3. Sales and Marketing
  4. Operations
  5. Finance

From these elements, you can start building out more complex information specifically for your cultivation business.

Cannabis Manufacturing

Some points to think about when you develop your business plan is how your crop will be manufactured and transformed into useful products for the marketplace. At QSP Sciences, we have training for cannabis manufacturing, though, you need to learn to apply your know-how into useful methodologies for production-purposes.

Capture the Right Data for Your Venture

There are numerous options in the industry for finding relevant information to help you make decisions with your hemp business. Our company provides cannabis lab data training if you are in need to find to get started in analysis to move your brand forward.

Other tools might include sites, like, Google Trends which can help you pin-point certain trends happening now. For example, below is graph for the trend of “CBD”.

Assistance During the Process

If you ever need assistance for helping to steer your venture in the right direction, we offer consulting services which are especially useful to help you get started with cannabis extraction processes for including into your plan.

About QSP

Our company has been helping business owners back-up their claims with verifiable results and we look forward to continue to build on our good reputation in the industry. If you are in need of assistance with your business, please contact us and see if we can help you succeed!